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Deep-learning augmented RNA-seq analysis of transcript splicing

A major limitation for RNA-seq analysis of alternative splicing is its reliance on high sequencing coverage. We report DARTS (https://github.com/Xinglab/DARTS), a computational framework that integrates deep learning-based predictions with empirical RNA-seq evidence to infer differential alternative...

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Detalles Bibliográficos
Autores principales: Zhang, Zijun, Pan, Zhicheng, Ying, Yi, Xie, Zhijie, Adhikari, Samir, Phillips, John, Carstens, Russ P., Black, Douglas L., Wu, Yingnian, Xing, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605494/
https://www.ncbi.nlm.nih.gov/pubmed/30923373
http://dx.doi.org/10.1038/s41592-019-0351-9