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Deep-learning augmented RNA-seq analysis of transcript splicing
A major limitation for RNA-seq analysis of alternative splicing is its reliance on high sequencing coverage. We report DARTS (https://github.com/Xinglab/DARTS), a computational framework that integrates deep learning-based predictions with empirical RNA-seq evidence to infer differential alternative...
Autores principales: | Zhang, Zijun, Pan, Zhicheng, Ying, Yi, Xie, Zhijie, Adhikari, Samir, Phillips, John, Carstens, Russ P., Black, Douglas L., Wu, Yingnian, Xing, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605494/ https://www.ncbi.nlm.nih.gov/pubmed/30923373 http://dx.doi.org/10.1038/s41592-019-0351-9 |
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