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Persistence of an intact HIV reservoir in phenotypically naive T cells

Despite the efficacy of antiretroviral therapy (ART), HIV persists in a latent form and remains a hurdle to eradication. CD4(+) T lymphocytes harbor the majority of the HIV reservoir, but the role of individual subsets remains unclear. CD4(+) T cells were sorted into central, transitional, effector...

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Detalles Bibliográficos
Autores principales: Venanzi Rullo, Emmanuele, Pinzone, Marilia Rita, Cannon, LaMont, Weissman, Sam, Ceccarelli, Manuela, Zurakowski, Ryan, Nunnari, Giuseppe, O’Doherty, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605525/
https://www.ncbi.nlm.nih.gov/pubmed/33055422
http://dx.doi.org/10.1172/jci.insight.133157