Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation

Although congenital heart defects (CHDs) represent the most common birth defect, a comprehensive understanding of disease etiology remains unknown. This is further complicated since CHDs can occur in isolation or as a feature of another disorder. Analyzing disorders with associated CHDs provides a p...

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Detalles Bibliográficos
Autores principales: Lu, Po-Nien, Moreland, Trevor, Christian, Courtney J., Lund, Troy C., Steet, Richard A., Flanagan-Steet, Heather
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605527/
https://www.ncbi.nlm.nih.gov/pubmed/33055423
http://dx.doi.org/10.1172/jci.insight.133019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605527/
https://www.ncbi.nlm.nih.gov/pubmed/33055423
http://dx.doi.org/10.1172/jci.insight.133019

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