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Assessment of HIV-1 integration in tissues and subsets across infection stages

The integration of HIV DNA into the host genome contributes to lifelong infection in most individuals. Few studies have examined integration in lymphoid tissue, where HIV predominantly persists before and after antiretroviral treatment (ART). Of particular interest is whether integration site distri...

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Detalles Bibliográficos
Autores principales: Wu, Vincent H., Nobles, Christopher L., Kuri-Cervantes, Leticia, McCormick, Kevin, Everett, John K., Nguyen, Son, del Rio Estrada, Perla M., González-Navarro, Mauricio, Torres-Ruiz, Fernanda, Ávila-Ríos, Santiago, Reyes-Terán, Gustavo, Bushman, Frederic D., Betts, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605534/
https://www.ncbi.nlm.nih.gov/pubmed/32970634
http://dx.doi.org/10.1172/jci.insight.139783