Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain

A critical response to lysosomal membrane permeabilization (LMP) is the clearance of damaged lysosomes through a selective form of macroautophagy known as lysophagy. Although regulators of this process are emerging, whether organ- and cell-specific components contribute to the control of lysophagy r...

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Detalles Bibliográficos
Autores principales: Liu, Elaine A., Schultz, Mark L., Mochida, Chisaki, Chung, Chan, Paulson, Henry L., Lieberman, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605537/
https://www.ncbi.nlm.nih.gov/pubmed/32931479
http://dx.doi.org/10.1172/jci.insight.136676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605537/
https://www.ncbi.nlm.nih.gov/pubmed/32931479
http://dx.doi.org/10.1172/jci.insight.136676

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