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Pathogenic and therapeutic role for NRF2 signaling in ultraviolet light–induced skin pigmentation

Mottled skin pigmentation and solar lentigines from chronic photodamage with aging involve complex interactions between keratinocytes and melanocytes. However, the precise signaling mechanisms that could serve as therapeutic targets are unclear. Herein, we report that expression of nuclear factor er...

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Detalles Bibliográficos
Autores principales: Kerns, Michelle L., Miller, Robert J., Mazhar, Momina, Byrd, Angel S., Archer, Nathan K., Pinkser, Bret L., Lew, Lance, Dillen, Carly A., Wang, Ruizhi, Miller, Lloyd S., Chien, Anna L., Kang, Sewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605539/
https://www.ncbi.nlm.nih.gov/pubmed/33001866
http://dx.doi.org/10.1172/jci.insight.139342