PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis

Loss-of-function variants of protein tyrosine phosphatase non-receptor type 2 (PTPN2) enhance risk of inflammatory bowel disease and rheumatoid arthritis; however, whether the association between PTPN2 and autoimmune arthritis depends on gut inflammation is unknown. Here we demonstrate that inductio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Wan-Chen, Svensson, Mattias N.D., Zoccheddu, Martina, Tremblay, Michael L., Sakaguchi, Shimon, Stanford, Stephanie M., Bottini, Nunzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605542/
https://www.ncbi.nlm.nih.gov/pubmed/33055428
http://dx.doi.org/10.1172/jci.insight.141868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605542/
https://www.ncbi.nlm.nih.gov/pubmed/33055428
http://dx.doi.org/10.1172/jci.insight.141868

Ejemplares similares