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PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis

Loss-of-function variants of protein tyrosine phosphatase non-receptor type 2 (PTPN2) enhance risk of inflammatory bowel disease and rheumatoid arthritis; however, whether the association between PTPN2 and autoimmune arthritis depends on gut inflammation is unknown. Here we demonstrate that inductio...

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Detalles Bibliográficos
Autores principales:	Hsieh, Wan-Chen, Svensson, Mattias N.D., Zoccheddu, Martina, Tremblay, Michael L., Sakaguchi, Shimon, Stanford, Stephanie M., Bottini, Nunzio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605542/ https://www.ncbi.nlm.nih.gov/pubmed/33055428 http://dx.doi.org/10.1172/jci.insight.141868

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