Cargando…

Mechanism of ligand recognition by human ACE2 receptor

Angiotensin converting enzyme 2 (ACE2) plays a key role in renin-angiotensin system regulation and amino acid homeostasis. Human ACE2 acts as the receptor for severe acute respiratory syndrome coronaviruses SARS-CoV and SARS-CoV-2. ACE2 is also widely expressed in epithelial cells of lungs, heart, k...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattarai, Apurba, Pawnikar, Shristi, Miao, Yinglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605550/
https://www.ncbi.nlm.nih.gov/pubmed/33140043
http://dx.doi.org/10.1101/2020.10.30.362749