SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

During the evolution of SARS-CoV-2 in humans a D614G substitution in the spike (S) protein emerged and became the predominant circulating variant (S-614G) of the COVID-19 pandemic(1). However, whether the increasing prevalence of the S-614G variant represents a fitness advantage that improves replic...

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Detalles Bibliográficos
Autores principales: Zhou, Bin, Thao, Tran Thi Nhu, Hoffmann, Donata, Taddeo, Adriano, Ebert, Nadine, Labroussaa, Fabien, Pohlmann, Anne, King, Jacqueline, Portmann, Jasmine, Halwe, Nico Joel, Ulrich, Lorenz, Trüeb, Bettina Salome, Kelly, Jenna N., Fan, Xiaoyu, Hoffmann, Bernd, Steiner, Silvio, Wang, Li, Thomann, Lisa, Lin, Xudong, Stalder, Hanspeter, Pozzi, Berta, de Brot, Simone, Jiang, Nannan, Cui, Dan, Hossain, Jaber, Wilson, Malania, Keller, Matthew, Stark, Thomas J., Barnes, John R., Dijkman, Ronald, Jores, Joerg, Benarafa, Charaf, Wentworth, David E., Thiel, Volker, Beer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605563/
https://www.ncbi.nlm.nih.gov/pubmed/33140052
http://dx.doi.org/10.1101/2020.10.27.357558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605563/
https://www.ncbi.nlm.nih.gov/pubmed/33140052
http://dx.doi.org/10.1101/2020.10.27.357558

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