Cargando…

Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression, and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays an integral role in regulating vascular barrier function physio...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li, Astone, Matteo, Alam, Sk. Kayum, Zhu, Zhu, Pei, Wuhong, Frank, David A., Burgess, Shawn M., Hoeppner, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605565/
https://www.ncbi.nlm.nih.gov/pubmed/33140053
http://dx.doi.org/10.1101/2020.10.27.358374