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Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression, and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays an integral role in regulating vascular barrier function physio...
Autores principales: | Wang, Li, Astone, Matteo, Alam, Sk. Kayum, Zhu, Zhu, Pei, Wuhong, Frank, David A., Burgess, Shawn M., Hoeppner, Luke H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605565/ https://www.ncbi.nlm.nih.gov/pubmed/33140053 http://dx.doi.org/10.1101/2020.10.27.358374 |
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