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ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility

Angiotensin-converting enzyme-2 (ACE2) receptor has been identified as the key adhesion molecule for the transmission of the SARS-CoV-2. However, there is no evidence that human genetic variation in ACE2 is singularly responsible for COVID-19 susceptibility. Therefore, we performed a multi-level cha...

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Detalles Bibliográficos
Autores principales: Pathak, Gita A, Wendt, Frank R, Goswami, Aranyak, Angelis, Flavio De, Polimanti, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605570/
https://www.ncbi.nlm.nih.gov/pubmed/33140059
http://dx.doi.org/10.1101/2020.10.27.20220665