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The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors

Over the last 2 decades, several coronaviruses (CoVs) have crossed the species barrier into humans, causing highly prevalent and severe respiratory diseases, often with fatal outcomes. CoVs are a large group of enveloped, single-stranded, positive-sense RNA viruses, which encode large replicase poly...

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Detalles Bibliográficos
Autores principales: Pišlar, Anja, Mitrović, Ana, Sabotič, Jerica, Pečar Fonović, Urša, Perišić Nanut, Milica, Jakoš, Tanja, Senjor, Emanuela, Kos, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605623/
https://www.ncbi.nlm.nih.gov/pubmed/33137165
http://dx.doi.org/10.1371/journal.ppat.1009013