Targeting Yes1 Associated Transcriptional Regulator Inhibits Hepatocellular Carcinoma Progression and Improves Sensitivity to Sorafenib: An in vitro and in vivo Study

PURPOSE: The aim of this study was to investigate the role of Yes1 associated transcriptional regulator (YAP1) in the pathology of hepatocellular carcinoma (HCC) and its potential as a therapeutic target. METHODS: YAP1 expression in HCC and adjacent tissues was determined via immunohistochemistry; i...

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Detalles Bibliográficos
Autores principales: Guo, Liwen, Zheng, Jiaping, Luo, Jun, Zhang, Zhewei, Shao, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605682/
https://www.ncbi.nlm.nih.gov/pubmed/33149619
http://dx.doi.org/10.2147/OTT.S249412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605682/
https://www.ncbi.nlm.nih.gov/pubmed/33149619
http://dx.doi.org/10.2147/OTT.S249412

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