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Targeting Yes1 Associated Transcriptional Regulator Inhibits Hepatocellular Carcinoma Progression and Improves Sensitivity to Sorafenib: An in vitro and in vivo Study
PURPOSE: The aim of this study was to investigate the role of Yes1 associated transcriptional regulator (YAP1) in the pathology of hepatocellular carcinoma (HCC) and its potential as a therapeutic target. METHODS: YAP1 expression in HCC and adjacent tissues was determined via immunohistochemistry; i...
Autores principales: | Guo, Liwen, Zheng, Jiaping, Luo, Jun, Zhang, Zhewei, Shao, Guoliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605682/ https://www.ncbi.nlm.nih.gov/pubmed/33149619 http://dx.doi.org/10.2147/OTT.S249412 |
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