Docosahexaenoic acid inhibits the proliferation of Kras/TP53 double mutant pancreatic ductal adenocarcinoma cells through modulation of glutathione level and suppression of nucleotide synthesis

The treatment of cancer cells obtained by blocking cellular metabolism has received a lot of attention recently. Previous studies have demonstrated that Kras mutation-mediated abnormal glucose metabolism would lead to an aberrant cell proliferation in human pancreatic ductal adenocarcinoma (PDAC) ce...

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Detalles Bibliográficos
Autores principales: Hung, Wei-Chia, Lee, Der-Yen, Chiang, En-Pei Isabel, Syu, Jia-Ning, Chao, Che-Yi, Yang, Mei-Due, Tsai, Shu-Yao, Tang, Feng-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605869/
https://www.ncbi.nlm.nih.gov/pubmed/33137095
http://dx.doi.org/10.1371/journal.pone.0241186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605869/
https://www.ncbi.nlm.nih.gov/pubmed/33137095
http://dx.doi.org/10.1371/journal.pone.0241186

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