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Burkholderia pseudomallei triggers canonical inflammasome activation in a human primary macrophage-based infection model

Most of the current knowledge on Burkholderia pseudomallei-induced inflammasome activation and cell death in macrophages is derived from murine systems. Little is known about the involved bacterial structures and mechanisms in primary human macrophages. This is of particular relevance since murine a...

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Detalles Bibliográficos
Autores principales: Lichtenegger, Sabine, Stiehler, Julia, Saiger, Sabine, Zauner, Andrea, Kleinhappl, Barbara, Bernecker, Claudia, Schlenke, Peter, Wagner, Gabriel E., Krause, Kathrin, Gastager, Magdalena, Steinmetz, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605897/
https://www.ncbi.nlm.nih.gov/pubmed/33137811
http://dx.doi.org/10.1371/journal.pntd.0008840