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Impact of molecular weight on the mechanism of cellular uptake of polyethylene glycols (PEGs) with particular reference to P-glycoprotein

Polyethylene glycols (PEGs) in general use are polydisperse molecules with molecular weight (MW) distributed around an average value applied in their designation e.g., PEG 4000. Previous research has shown that PEGs can act as P-glycoprotein (P-gp) inhibitors with the potential to affect the absorpt...

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Detalles Bibliográficos
Autores principales: Wang, Tingting, Guo, Yingjie, He, Yang, Ren, Tianming, Yin, Lei, Fawcett, John Paul, Gu, Jingkai, Sun, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606107/
https://www.ncbi.nlm.nih.gov/pubmed/33163350
http://dx.doi.org/10.1016/j.apsb.2020.02.001