Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1

Cancer immunotherapy is revolutionizing oncology and has emerged as a promising strategy for the treatment of multiple cancers. Indoleamine 2,3-dioxygenase 1 (IDO1), an immune checkpoint, plays an important role in tumor immune escape through the regulation of multiple immune cells and has been rega...

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Detalles Bibliográficos
Autores principales: Hu, Mingxing, Zhou, Weilin, Wang, Yijie, Yao, Dongping, Ye, Tinghong, Yao, Yuqin, Chen, Bin, Liu, Gongping, Yang, Xifei, Wang, Wei, Xie, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606109/
https://www.ncbi.nlm.nih.gov/pubmed/33163345
http://dx.doi.org/10.1016/j.apsb.2020.02.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606109/
https://www.ncbi.nlm.nih.gov/pubmed/33163345
http://dx.doi.org/10.1016/j.apsb.2020.02.010

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