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Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS

Neuraminidase inhibitors (NAIs) are the mainstay antiviral drugs against influenza infection. In this study, a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads (NA-MB). After verifying the feasibility of NA-MB with an artificial mixture including NA...

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Detalles Bibliográficos
Autores principales: Luo, Sifan, Guo, Linbo, Sheng, Caimin, Zhao, Yumei, Chen, Ling, Li, Chufang, Jiang, Zhengjin, Tian, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606179/
https://www.ncbi.nlm.nih.gov/pubmed/33163339
http://dx.doi.org/10.1016/j.apsb.2020.04.001