Mesenchymal PGD(2) activates an ILC2-Treg axis to promote proliferation of normal and malignant HSPCs

Cyclooxygenase (COX)-dependent production of prostaglandins (PGs) is known to play important roles in tumorigenesis. PGD(2) has recently emerged as a key regulator of tumor- and inflammation-associated functions. Here we show that mesenchymal stromal cells (MSCs) from patients with acute myeloid leu...

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Detalles Bibliográficos
Autores principales: Wu, Limei, Lin, Qiqi, Ma, Zhilin, Chowdhury, Fabliha Ahmed, Mazumder, Md Habibul Hasan, Du, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606225/
https://www.ncbi.nlm.nih.gov/pubmed/32366935
http://dx.doi.org/10.1038/s41375-020-0843-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606225/
https://www.ncbi.nlm.nih.gov/pubmed/32366935
http://dx.doi.org/10.1038/s41375-020-0843-8

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