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Therapeutic Potential of Apatinib Against Colorectal Cancer by Inhibiting VEGFR2-Mediated Angiogenesis and β-Catenin Signaling

PURPOSE: Apatinib is an inhibitor of VEGFR2 (vascular endothelial growth factor receptor 2) that has attracted a great deal of attention due to its promotion of anticancer activity. In the present study, we investigated the therapeutic effects of apatinib against colorectal cancer (CRC) and examined...

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Detalles Bibliográficos
Autores principales: Cai, Xiaomin, Wei, Bin, Li, Lele, Chen, Xiaofeng, Yang, Jing, Li, Xiaofei, Jiang, Xiaozheng, Lv, Mu, Li, Mingyang, Lin, Yumeng, Xu, Qiang, Guo, Wenjie, Gu, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606303/
https://www.ncbi.nlm.nih.gov/pubmed/33154652
http://dx.doi.org/10.2147/OTT.S266549