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Response Surface Methodology for Statistical Optimization of Chitosan/Alginate Nanoparticles as a Vehicle for Recombinant Human Bone Morphogenetic Protein-2 Delivery

PURPOSE: In this study, chitosan/alginate nanoparticles are prospected as a carrier for controlled release of recombinant human bone morphogenetic protein-2 (rhBMP-2). MATERIALS AND METHODS: The rhBMP-2-loaded chitosan/alginate nanoparticles (Cs/Alg/B NPs) were prepared using the ionic gelation (IG)...

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Detalles Bibliográficos
Autores principales: Zohri, Maryam, Akbari Javar, Hamid, Gazori, Taraneh, Khoshayand, Mohammad Reza, Aghaee-Bakhtiari, Seyed Hamid, Ghahremani, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606360/
https://www.ncbi.nlm.nih.gov/pubmed/33154637
http://dx.doi.org/10.2147/IJN.S250630