Cargando…

Nimodipine improves cortical efficiency during working memory in healthy subjects

The L-type calcium channel gene, CACNA1C, is a validated risk gene for schizophrenia and the target of calcium channel blockers. Carriers of the risk-associated genotype (rs1006737 A allele) have increased frontal cortical activity during working memory and higher CACNA1C mRNA expression in the pref...

Descripción completa

Detalles Bibliográficos
Autores principales: Zink, Caroline F., Giegerich, Mellissa, Prettyman, Greer E., Carta, Kayla E., van Ginkel, Marcus, O’Rourke, Molly P., Singh, Eesha, Fuchs, Edward J., Hendrix, Craig W., Zimmerman, Eric, Breakey, Jennifer, Marzinke, Mark A., Hummert, Pamela, Pillai, Jay J., Weinberger, Daniel R., Bigos, Kristin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606375/
https://www.ncbi.nlm.nih.gov/pubmed/33139710
http://dx.doi.org/10.1038/s41398-020-01066-z