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Nimodipine improves cortical efficiency during working memory in healthy subjects
The L-type calcium channel gene, CACNA1C, is a validated risk gene for schizophrenia and the target of calcium channel blockers. Carriers of the risk-associated genotype (rs1006737 A allele) have increased frontal cortical activity during working memory and higher CACNA1C mRNA expression in the pref...
Autores principales: | Zink, Caroline F., Giegerich, Mellissa, Prettyman, Greer E., Carta, Kayla E., van Ginkel, Marcus, O’Rourke, Molly P., Singh, Eesha, Fuchs, Edward J., Hendrix, Craig W., Zimmerman, Eric, Breakey, Jennifer, Marzinke, Mark A., Hummert, Pamela, Pillai, Jay J., Weinberger, Daniel R., Bigos, Kristin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606375/ https://www.ncbi.nlm.nih.gov/pubmed/33139710 http://dx.doi.org/10.1038/s41398-020-01066-z |
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