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Whole genome integrity and enhanced developmental potential in ram freeze-dried spermatozoa at mild sub-zero temperature

Freeze-dried spermatozoa typically shows a reduction in fertility primarily due to the DNA damage resulting from the sublimation process. In order to minimize the physical/mechanical damage resulting from lyophilization, here we focused on the freezing phase, comparing two cooling protocols: (i) rap...

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Detalles Bibliográficos
Autores principales: Palazzese, Luca, Anzalone, Debora Agata, Turri, Federica, Faieta, Marco, Donnadio, Anna, Pizzi, Flavia, Pittia, Paola, Matsukawa, Kazutsugu, Loi, Pasqualino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606492/
https://www.ncbi.nlm.nih.gov/pubmed/33139842
http://dx.doi.org/10.1038/s41598-020-76061-x