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The Role of Antibodies in the Pathogenesis of Multiple Sclerosis

The presence of persistent intrathecal oligoclonal immunoglobulin G (IgG) bands (OCBs) and lesional IgG deposition are seminal features of multiple sclerosis (MS) disease pathology. Despite extensive investigations, the role of antibodies, the products of mature CD19(+) B cells, in disease developme...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoli, Graner, Michael, Kennedy, Peter G. E., Liu, Yiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606501/
https://www.ncbi.nlm.nih.gov/pubmed/33192968
http://dx.doi.org/10.3389/fneur.2020.533388