ESCRT-III controls nuclear envelope deformation induced by progerin

Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder, caused by mutation in the gene encoding lamin A/C, which produces a truncated protein called progerin. In cells from HGPS patients, progerin accumulates at the nuclear membrane (NM), where it causes NM deformations. In this s...

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Detalles Bibliográficos
Autores principales: Arii, Jun, Maeda, Fumio, Maruzuru, Yuhei, Koyanagi, Naoto, Kato, Akihisa, Mori, Yasuko, Kawaguchi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606583/
https://www.ncbi.nlm.nih.gov/pubmed/33139753
http://dx.doi.org/10.1038/s41598-020-75852-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606583/
https://www.ncbi.nlm.nih.gov/pubmed/33139753
http://dx.doi.org/10.1038/s41598-020-75852-6

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