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Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone

Advanced glycation end-products (AGEs) deteriorate bone strength. Among over 40 species identified in vivo, AGEs other than pentosidine were roughly estimated as total fluorescent AGEs (tfAGEs) due to technical difficulties. Using LC-QqTOF-MS, we established a system that enabled the quantitation of...

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Detalles Bibliográficos
Autores principales: Arakawa, Shoutaro, Suzuki, Ryusuke, Kurosaka, Daisaburo, Ikeda, Ryo, Hayashi, Hiroteru, Kayama, Tomohiro, Ohno, Rei-ichi, Nagai, Ryoji, Marumo, Keishi, Saito, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606603/
https://www.ncbi.nlm.nih.gov/pubmed/33139851
http://dx.doi.org/10.1038/s41598-020-75923-8