Expression of a novel brain specific isoform of C3G is regulated during development

Mice lacking C3G (RapGEF1), a ubiquitously expressed protein essential for neuronal differentiation, show multiple defects in brain development. Function of C3G in neurogenesis is poorly defined. Here, we identify brain specific expression of a novel C3G isoform in mice and humans. This isoform has...

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Detalles Bibliográficos
Autores principales: Sriram, Divya, Chintala, Ramulu, Parthasaradhi, B. V. V., Nayak, Sanjeev Chavan, Mariappan, Indumathi, Radha, Vegesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606606/
https://www.ncbi.nlm.nih.gov/pubmed/33139841
http://dx.doi.org/10.1038/s41598-020-75813-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606606/
https://www.ncbi.nlm.nih.gov/pubmed/33139841
http://dx.doi.org/10.1038/s41598-020-75813-z

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