Climbing fiber synapses rapidly and transiently inhibit neighboring Purkinje cells via ephaptic coupling

Climbing fibers (CFs) from the inferior olive (IO) make strong excitatory synapses onto cerebellar Purkinje cell (PC) dendrites, and trigger distinctive responses known as complex spikes (CSs). We find that in awake mice, a CS in one PC suppresses conventional simple spikes (SSs) in neighboring PCs...

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Detalles Bibliográficos
Autores principales: Han, Kyung-Seok, Chen, Christopher H., Khan, Mehak M., Guo, Chong, Regehr, Wade G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606706/
https://www.ncbi.nlm.nih.gov/pubmed/32895566
http://dx.doi.org/10.1038/s41593-020-0701-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606706/
https://www.ncbi.nlm.nih.gov/pubmed/32895566
http://dx.doi.org/10.1038/s41593-020-0701-z

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