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The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury

Sepsis is the major cause of acute kidney injury (AKI) associated with high mortality rates. Mitochondrial dysfunction contributes to the pathophysiology of septic AKI. Mitophagy is an important mitochondrial quality control mechanism that selectively eliminates damaged mitochondria, but its role an...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Zhu, Jiefu, Liu, Zhiwen, Shu, Shaoqun, Fu, Ying, Liu, Yuxue, Cai, Juan, Tang, Chengyuan, Liu, Yu, Yin, Xiaoming, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606859/
https://www.ncbi.nlm.nih.gov/pubmed/33137712
http://dx.doi.org/10.1016/j.redox.2020.101767