Influence of Intratumor Heterogeneity on the Predictivity of MGMT Gene Promoter Methylation Status in Glioblastoma

Glioblastoma is the most aggressive tumor of the central nervous system. Prognosis is poor, even in the presence of a methylated state of MGMT gene promoter, which represents the biomarker with the highest prognostic/predictive value for the standard treatment of patients. Among patients with a meth...

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Detalles Bibliográficos
Autores principales: Brigliadori, Giovanni, Goffredo, Giulia, Bartolini, Daniela, Tosatto, Luigino, Gurrieri, Lorena, Mercatali, Laura, Ibrahim, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606920/
https://www.ncbi.nlm.nih.gov/pubmed/33194592
http://dx.doi.org/10.3389/fonc.2020.533000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606920/
https://www.ncbi.nlm.nih.gov/pubmed/33194592
http://dx.doi.org/10.3389/fonc.2020.533000

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