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Network Simulations Reveal Molecular Signatures of Vulnerability to Age-Dependent Stress and Tau Accumulation

Alzheimer’s disease (AD) is the leading cause of dementia and one of the most common causes of death worldwide. As an age-dependent multifactorial disease, the causative triggers of AD are rooted in spontaneous declines in cellular function and metabolic capacity with increases in protein stressors...

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Detalles Bibliográficos
Autores principales: Hoffman, Timothy E., Hanneman, William H., Moreno, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606936/
https://www.ncbi.nlm.nih.gov/pubmed/33195439
http://dx.doi.org/10.3389/fmolb.2020.590045