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Surgical and Systemic Treatment of Hereditary Breast Cancer: A Mini-Review With a Focus on BRCA1 and BRCA2 Mutations

Hereditary breast cancer accounts for 5%–10% of breast cancer cases. The majority of familial cases have been linked to germline mutations in BRCA1 and BRCA2 genes, though other high penetrance susceptibility genes have also been identified through genomic testing advances. Optimal surgical treatmen...

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Detalles Bibliográficos
Autores principales: Pouptsis, Athanasios, Swafe, Leyla, Patwardhan, Maneesha, Stavraka, Chara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607003/
https://www.ncbi.nlm.nih.gov/pubmed/33194613
http://dx.doi.org/10.3389/fonc.2020.553080