Activation of autophagy during farnesyl pyrophosphate synthase inhibition is mediated through PI3K/AKT/mTOR signaling

OBJECTIVES: Autophagy is divided into three phases: autophagosome engulfment of intracellular organelles and proteins, autophagosome fusion with lysosomes, and autolysosome degradation. The farnesyl pyrophosphate synthase inhibitor ibandronate (IBAN) has in vivo cardioprotective properties, potentia...

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Detalles Bibliográficos
Autores principales: Han, Jie, Huang, Chaoyang, Jiang, Jiukun, Jiang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607048/
https://www.ncbi.nlm.nih.gov/pubmed/31884848
http://dx.doi.org/10.1177/0300060519875371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607048/
https://www.ncbi.nlm.nih.gov/pubmed/31884848
http://dx.doi.org/10.1177/0300060519875371

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