Telomerase reverse transcriptase promoter mutations in thyroid carcinomas: implications in precision oncology—a narrative review

Telomerase is a ribonucleoprotein enzyme with telomerase reverse transcriptase (TERT) as a catalytic component. In normal human follicular thyroid cells or thyrocytes, telomerase is silent due to the TERT gene being tightly repressed. However, during the formation of thyroid carcinoma (TC), telomera...

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Detalles Bibliográficos
Autores principales: Yuan, Xiaotian, Liu, Tiantian, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607115/
https://www.ncbi.nlm.nih.gov/pubmed/33178776
http://dx.doi.org/10.21037/atm-20-5024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607115/
https://www.ncbi.nlm.nih.gov/pubmed/33178776
http://dx.doi.org/10.21037/atm-20-5024

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