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Epithelial/mesenchymal heterogeneity of high‐grade serous ovarian carcinoma samples correlates with miRNA let‐7 levels and predicts tumor growth and metastasis

Patient‐derived samples present an advantage over current cell line models of high‐grade serous ovarian cancer (HGSOC) that are not always reliable and phenotypically faithful models of in vivo HGSOC. To improve upon cell line models of HGSOC, we set out to characterize a panel of patient‐derived ce...

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Detalles Bibliográficos
Autores principales: Chirshev, Evgeny, Hojo, Nozomi, Bertucci, Antonella, Sanderman, Linda, Nguyen, Anthony, Wang, Hanmin, Suzuki, Tise, Brito, Emmanuel, Martinez, Shannalee R., Castañón, Christine, Mirshahidi, Saied, Vazquez, Marcelo E., Wat, Pamela, Oberg, Kerby C., Ioffe, Yevgeniya J., Unternaehrer, Juli J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607177/
https://www.ncbi.nlm.nih.gov/pubmed/32652647
http://dx.doi.org/10.1002/1878-0261.12762