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Epigenetic–smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early‐stage NSCLC patients

Tripartite motif containing 27 (TRIM27) is highly expressed in lung cancer, including non‐small‐cell lung cancer (NSCLC). Here, we profiled DNA methylation of lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tumours from 613 early‐stage NSCLC patients and evaluated associations bet...

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Detalles Bibliográficos
Autores principales: Ji, Xinyu, Lin, Lijuan, Shen, Sipeng, Dong, Xuesi, Chen, Chao, Li, Yi, Zhu, Ying, Huang, Hui, Chen, Jiajin, Chen, Xin, Wei, Liangmin, He, Jieyu, Duan, Weiwei, Su, Li, Jiang, Yue, Fan, Juanjuan, Guan, Jinxing, You, Dongfang, Shafer, Andrea, Bjaanæs, Maria Moksnes, Karlsson, Anna, Planck, Maria, Staaf, Johan, Helland, Åslaug, Esteller, Manel, Wei, Yongyue, Zhang, Ruyang, Chen, Feng, Christiani, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607178/
https://www.ncbi.nlm.nih.gov/pubmed/33448640
http://dx.doi.org/10.1002/1878-0261.12785