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Expression of HGF, pMet, and pAkt is related to benefit of radiotherapy after breast‐conserving surgery: a long‐term follow‐up of the SweBCG91‐RT randomised trial

Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the risk of ipsilateral breast tumour recurrence (IBTR) a...

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Detalles Bibliográficos
Autores principales: Sjöström, Martin, Veenstra, Cynthia, Holmberg, Erik, Karlsson, Per, Killander, Fredrika, Malmström, Per, Niméus, Emma, Fernö, Mårten, Stål, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607179/
https://www.ncbi.nlm.nih.gov/pubmed/32946618
http://dx.doi.org/10.1002/1878-0261.12803