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Association of MTHFR and RFC1 gene polymorphisms with methotrexate efficacy and toxicity in Chinese Han patients with rheumatoid arthritis

OBJECTIVE: The objective was to explore the association of methylene tetrahydrofolate reductase (MTHFR) C667T and A1298C and reduced folate carrier 1 (RFC-1) A80G single nucleotide polymorphisms (SNP) with rheumatoid arthritis (RA) and efficacy and toxicity of methotrexate (MTX) treatment in Chinese...

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Detalles Bibliográficos
Autores principales: Wang, Shengli, Zuo, Shuguang, Liu, Zhigang, Ji, Xinying, Yao, Zhenqiang, Wang, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607194/
https://www.ncbi.nlm.nih.gov/pubmed/31617429
http://dx.doi.org/10.1177/0300060519879588