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The circadian rhythm and core gene Period2 regulate the chemotherapy effect and multidrug resistance of ovarian cancer through the PI3K signaling pathway

Background: Ovarian cancer is the most lethal cancer in the female reproductive system. It has been shown that ‘time chemotherapy’ of ovarian cancer has an important impact on the chemotherapy effect and prognosis of patients, but the specific mechanism is not known. Methods: We designed a case–cont...

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Detalles Bibliográficos
Autores principales: Wang, Zhaoxia, Wang, Honghong, Guo, Hongrui, Li, Fengyan, Wu, Weiwei, Zhang, Sanyuan, Wang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607197/
https://www.ncbi.nlm.nih.gov/pubmed/33083827
http://dx.doi.org/10.1042/BSR20202683