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Modelling the roles of antibody titre and avidity in protection from Plasmodium falciparum malaria infection following RTS,S/AS01 vaccination

Anti-circumsporozoite antibody titres have been established as an essential indicator for evaluating the immunogenicity and protective capacity of the RTS,S/AS01 malaria vaccine. However, a new delayed-fractional dose regime of the vaccine was recently shown to increase vaccine efficacy, from 62.5%...

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Detalles Bibliográficos
Autores principales: Thompson, Hayley A., Hogan, Alexandra B., Walker, Patrick G.T., White, Michael T., Cunnington, Aubrey J., Ockenhouse, Christian F., Ghani, Azra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607256/
https://www.ncbi.nlm.nih.gov/pubmed/33041104
http://dx.doi.org/10.1016/j.vaccine.2020.09.069