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Accelerated aging among childhood, adolescent, and young adult cancer survivors is evidenced by increased expression of p16(INK4a) and frailty

BACKGROUND: Cellular senescence, measured by expression of the cell cycle kinase inhibitor p16(INK4a), may contribute to accelerated aging in survivors of childhood, adolescent, and young adult cancer. The authors measured peripheral blood T‐lymphocyte p16(INK4a) expression among pediatric and young...

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Detalles Bibliográficos
Autores principales: Smitherman, Andrew B., Wood, William A., Mitin, Natalia, Ayer Miller, Vanessa L., Deal, Allison M., Davis, Ian J., Blatt, Julie, Gold, Stuart H., Muss, Hyman B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607511/
https://www.ncbi.nlm.nih.gov/pubmed/32830315
http://dx.doi.org/10.1002/cncr.33112