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Correcting for experiment-specific variability in expression compendia can remove underlying signals
MOTIVATION: In the past two decades, scientists in different laboratories have assayed gene expression from millions of samples. These experiments can be combined into compendia and analyzed collectively to extract novel biological patterns. Technical variability, or "batch effects," may r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607552/ https://www.ncbi.nlm.nih.gov/pubmed/33140829 http://dx.doi.org/10.1093/gigascience/giaa117 |