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Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression

BACKGROUND: Long noncoding enhancer RNAs (lnc-eRNAs) are a subset of stable eRNAs identified from annotated lncRNAs. They might act as enhancer activity-related therapeutic targets in cancer. However, the underlying mechanism of epigenetic activation and their function in cancer initiation and progr...

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Detalles Bibliográficos
Autores principales: Fang, Ke, Huang, Wei, Sun, Yu-Meng, Chen, Tian-Qi, Zeng, Zhan-Cheng, Yang, Qian-Qian, Pan, Qi, Han, Cai, Sun, Lin-Yu, Luo, Xue-Qun, Wang, Wen-Tao, Chen, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607629/
https://www.ncbi.nlm.nih.gov/pubmed/33143730
http://dx.doi.org/10.1186/s13059-020-02186-x