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Enhanced production of taxadiene in Saccharomyces cerevisiae
BACKGROUND: Cost-effective production of the highly effective anti-cancer drug, paclitaxel (Taxol(®)), remains limited despite growing global demands. Low yields of the critical taxadiene precursor remains a key bottleneck in microbial production. In this study, the key challenge of poor taxadiene s...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607689/ https://www.ncbi.nlm.nih.gov/pubmed/33138820 http://dx.doi.org/10.1186/s12934-020-01458-2 |