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Enhanced production of taxadiene in Saccharomyces cerevisiae

BACKGROUND: Cost-effective production of the highly effective anti-cancer drug, paclitaxel (Taxol(®)), remains limited despite growing global demands. Low yields of the critical taxadiene precursor remains a key bottleneck in microbial production. In this study, the key challenge of poor taxadiene s...

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Detalles Bibliográficos
Autores principales:	Nowrouzi, Behnaz, Li, Rachel A., Walls, Laura E., d’Espaux, Leo, Malcı, Koray, Liang, Lungang, Jonguitud-Borrego, Nestor, Lerma-Escalera, Albert I., Morones-Ramirez, Jose R., Keasling, Jay D., Rios-Solis, Leonardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607689/ https://www.ncbi.nlm.nih.gov/pubmed/33138820 http://dx.doi.org/10.1186/s12934-020-01458-2

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